Publications
My PhD has originally focused on characterizing the sequence environment of functional miRNA binding sites from statistical analyses of high-throughput genomics, transcriptomics and proteomics datasets. Since a year, I have been using the Bayesian framework and dynamical systems in order to model microRNA-mediated gene regulation.
In addition, as part of my research, I have been developing and applying different computational techniques in a variety of contexts such as neuroscience, the inference of gene regulatory networks, or more recently to the social network of the US senate.
Cosponsorship Communities in the U.S. Senate
Jean Hausser, Mark Rivera, Skyler Cranmer
Proceedings of the 2008 Santa Fe Institute Complex Systems Summer School
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Determinants of RISC binding and mRNA degradation
Jean Hausser, Markus Landthaler, Lukasz Jaskiewicz, Dimos Gaidatzis, Mihaela Zavolan
Genome Research 2009, 19:2009-2020
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Entropy inference and the James-Stein estimator, with application to nonlinear gene association networks
Inference of miRNA targets using evolutionary conservation and pathway analysis
Dimos Gaidatzis, Erik van Nimwegen, Jean Hausser, Mihaela Zavolan
BMC Bioinformatics 2007, 8:69
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miR-375 maintains normal pancreatic alpha- and beta-cell mass
Matthew N. Poy, Jean Hausser, Mirko Trajkovski, Matthias Braun, Stephan Collins, Patrick Rorsman, Mihaela Zavolan and Markus Stoffel
Proceedings of the National Academy of Sciences USA 2009, 106:5313
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MirZ: an integrated microRNA expression atlas and target prediction ressource
Jean Hausser, Philipp Berninger, Christoph Rodak, Yvonne Jantscher, Stefan Wirth, Mihaela Zavolan
Nucleic Acids Research 2009, 37:W266-272
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Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
Markus Hafner, Markus Landthaler, Lukas Burger, Mohsen Khorshid, Jean Hausser, Philipp Berninger, Andrea Rothballer, Manuel Ascano, Jr., Anna-Carina Jungkamp, Mathias Munschauer, Alexander Ulrich, Greg S. Wardle, Scott Dewell, Mihaela Zavolan, and Thomas Tuschl
Cell 2010, 141:129-141
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